Arterial-wall smooth-muscle-cell fibrous plates can catch fatty debris, clotted blood, and connective tissue {atherosclerosis}| {arteriosclerosis}, to make blobs {plaque}. If blobs break, blood clots can form, which later can stay or break off and block blood flow.
Statins decrease LDL.
Molecules {vascular cellular adhesion molecule-1} (VCAM-1) can attract monocytes and lymphocytes to epithelia and cause inflammation. Pyrrolidine dithiocarbamate anti-oxidant represses VCAM-1 gene. Lipid peroxide activates VCAM-1 gene.
Biological Sciences>Medicine>Disease>Kinds>Organ>Circulation>Blockage
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Date Modified: 2022.0224