In excitatory axons, conditioned stimulus (CS) allows calcium to enter axon terminal and release glutamate {presynaptic facilitation}. Unconditioned stimulus (UCS) releases serotonin from axon-to-axon axoaxonic synapses, which increase protein kinase A, which releases more glutamate. Association is non-Hebbian. More UCS also activates MAP kinase and expresses genes to make more glutamate synapses.
Biological Sciences>Zoology>Organ>Nerve>Neuron>Physiology
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Date Modified: 2022.0224