Receptor complexes {GABA receptor} {gamma-aminobutyric acid receptor} can bind GABA.
types
Type A {GABA-A receptor} is fast, opens chloride-ion channels, and inhibits. Type B {GABA-B receptor} is slow, opens potassium-ion channels, closes calcium-ion channels, uses IP3 and DAG, inhibits, and uses second-messenger system, probably cyclic AMP.
parts
Endogenous benzodiazepine-receptor protein is part of GABA-receptor complex and increases extent or period of GABA-operated chloride-ion channel opening.
drugs
Benzodiazepines and anxiety-reducing neuromodulators {anxiolytic drug, GABA} increase GABA affinity for GABA neuroreceptors and enhance GABA-mediated synaptic potentials. Perhaps, anesthetics bind to GABA-A. Perhaps, neurosteroids from progesterone and cholesterol bind to GABA-A.
Biological Sciences>Zoology>Organ>Nerve>Neural Chemical>Receptor
4-Zoology-Organ-Nerve-Neural Chemical-Receptor
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Date Modified: 2022.0224