Deinococcus radiodurans proteins {bacteriophytochrome}| can control gene expression, absorb red light, and fluoresce infrared light.
Stressed bacteria first try to repair damaged DNA {SOS response}. Then they derepress genes that make proteins that cause high mutation rates. Bacterial cells can attach RecA protein to single-stranded DNA, which splits LexA regulatory protein, which derepresses genes that cause DNA mutations, which alter drug targets.
Gene regions can make secretion proteins {type IV secretion system} (TFSS). TFSS can inject protein toxins into host cells. Helicobacter has CagA gene, which makes CagA protein. Helicobacter injects CagA protein into stomach-lining cells. CagA protein increases stomach-cancer probability. CagA changes and affects cell shape, secretion, and signaling. For example, host cells make cytokines.
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Date Modified: 2022.0225