Intravenous hypnotic drugs, such as propofol, barbiturates, and benzodiazepines, increase inhibition by keeping chloride channels open, because they enhance receptor inhibitory neurotransmitter effects {gamma-aminobutyric acid, drugs} (GABA) [Franks and Lieb, 2000]. Humans have more than 15 GABA-receptor types, which have different binding constants and connect to different pathways.
Drugs {etomidate} can enhance GABA-A receptors [Franks and Lieb, 2000].
Intravenous drugs {propofol} can affect GABA reception and correlate with low blood flow to midbrain and thalamus.
Intravenous barbiturates and sedatives {thiopental} {sodium pentothal} can affect GABA receptors [1930 to 1940].
4-Medicine-Drug-Kinds-Anesthetic
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Date Modified: 2022.0225