metastasis

Cancer cells can migrate {metastases} {metastasis}|. Migrating cancer cells go through blood-vessel walls and travel in blood and lymph {metastasize} until trapped in small blood vessels or lymph nodes. Cancer cells pass through capillary linings and start secondary tumors.

effects

Tumor cells can invade and destroy cell-cell adhesions, stromal extracellular matrix, basement membrane, and parenchymal cells. Cells deform. Cell motility increases. Cell receptors alter.

factors

Serine proteinase, cysteine proteinase, metalloproteinase can assist cancer invasion.

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Date Modified: 2022.0224