Large ribonucleotide and protein particles {spliceosome} perform splicing. Spliceosomes have U1 and U2 small nuclear ribonucleoproteins, U1 and U2 small nuclear ribonucleic acids, and SF2, U2AF, and other proteins. Intron 5' ends split first. Intermediate RNAs have lariat shapes, because introns bind to themselves with 2'-5' bonds. Enzymes cut 3' ends, and other enzymes join exon ends. Introns leave as lariats, because introns bind to themselves with 2'-5' bonds to make circles.
Biological Sciences>Genetics>Post-Transcription>Splicing
4-Genetics-Post-Transcription-Splicing
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Date Modified: 2022.0224