silent mutation

Codons, with same first two bases but different third base, can code for the same amino acid. For those codons, third-base mutations {silent mutation} do not make any difference to survival.

However, different codons bind to different t-RNAs, and some t-RNAs are more abundant than others. Times to bind scarcer t-RNA are longer than times for more abundant t-RNA. Time differences can affect protein folding, change protein structure, and affect function.

Silent mutations can accumulate and eventually encode new proteins. For example, mutations can cause body-part replication. Subsequent generations can modify replicated parts to make new structures and functions.

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