Cell-surface receptors can bind hormones and affect GTP-binding proteins {G protein} inside cell membranes. Activated G protein catalyzes its return to unactivated state, thus timing rate of G-protein processes. Immediate-early genes activated in learning use cAMP signal paths.
cyclic AMP
G protein uses GTP to activate adenylate cyclase and make cAMP. cAMP affects protein kinase A, which then phosphorylates CRE-binding protein, which binds to cAMP response elements (CRE).
senses
Olfactory sensors use G-protein transduction.
structure
G protein is similar to proteins for cross-membrane signaling, protein synthesis, cell molecule transport, and cross-membrane transport.
Biological Sciences>Genetics>Gene>Cell Surface Receptor>Binding
4-Genetics-Gene-Cell Surface Receptor-Binding
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Date Modified: 2022.0224