Techniques {DNA footprinting} can measure protein binding to DNA without measuring gene expression or protein synthesis. Protein binding to DNA sites prevents DNAase enzyme from cutting DNA. If protein binds to DNA, protein-DNA complex moves more slowly in gels than DNA with no protein {mobility-shift assay}, so slower moving fragments have bound proteins.
Biological Sciences>Genetics>DNA Regulation>Protein
4-Genetics-DNA Regulation-Protein
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Date Modified: 2022.0224